SCHEMBL30974232

CC[C@H](C)[C@H](NC(=O)[C@@H]1CCCN1)C(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	2/20	0.45

▸	ACE	P12821	3/20	0.44

▸	MME	P08473	1/20	0.44

▸	CPA1	P15085	1/20	0.44

▸	ACE2	Q9BYF1	1/20	0.44

▸	OPRD1	P41143	3/20	0.43

▸	OPRM1	P35372	2/20	0.43

▸	SRC	P12931	3/20	0.42

▸	NTSR1	P30989	1/20	0.42

▸	ANPEP	P15144	1/20	0.41

▸	LNPEP	Q9UIQ6	1/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30946065	0.89	KEAP1 (0.47)	RENACEMMECPA1ACE2
SCHEMBL31461879	0.89	REN (0.54)	RENOPRD1OPRM1
SCHEMBL30974306	0.89	NTSR1 (0.48)	RENOPRD1OPRM1NTSR1ANPEP
SCHEMBL31461931	0.84	REN (0.56)	RENOPRD1OPRM1
SCHEMBL29790109	0.83	REN (0.41)	REN
SCHEMBL2859114	0.83	REN (0.41)	REN
SCHEMBL2859120	0.83	REN (0.41)	REN
SCHEMBL31296206	0.82	CALCRL (0.51)	RENOPRD1OPRM1SRCANPEP
SCHEMBL30051852	0.82	REN (0.58)	RENACEMMECPA1ACE2
SCHEMBL29518445	0.82	KEAP1 (0.53)	RENOPRD1OPRM1NTSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024132726-A1	SERUM PEPTIDE PATTERNS FOR DIAGNOSTICS OF ACUTE ISCHEMIC STROKE IN HUMANS AND DIFFERENTIAL DIAGNOSIS OF ACUTE ISCHEMIC STROKE FROM INTRACRANIAL HEMORRHAGIC STROKE	UNIWERSYTET GDANSKI (PL)	2024-06-27	—	—	WO	disclosed