Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.52 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 5/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.48 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.47 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29742976 | 0.88 | MAPK8 (0.63) | KEAP1MAPK8MAPK9MAPK10 | |
| SCHEMBL31104091 | 0.83 | REN (0.58) | RENNTSR1NTSR2 | |
| SCHEMBL31514352 | 0.83 | BECN1 (0.56) | KEAP1MAPK8MAPK9MAPK10F2 | |
| SCHEMBL30733440 | 0.83 | REN (0.64) | KEAP1MAPK8MAPK9MAPK10REN | |
| SCHEMBL30726561 | 0.82 | KEAP1 (0.68) | KEAP1MAPK8MAPK9MAPK10REN | |
| SCHEMBL30906522 | 0.82 | MAPK8 (0.67) | KEAP1MAPK8MAPK9MAPK10 | |
| SCHEMBL30974232 | 0.82 | REN (0.45) | RENOPRM1OPRD1NTSR1 | |
| SCHEMBL30906421 | 0.81 | KEAP1 (0.68) | KEAP1MAPK8MAPK9MAPK10 | |
| SCHEMBL30692048 | 0.81 | OPRM1 (0.56) | OPRM1OPRD1OPRK1KISS1R | |
| SCHEMBL30123020 | 0.81 | CALCRL (0.49) | RENOPRD1KISS1RNTSR2CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213544-B | Anisotropic antibody blocker HBR-7 and preparation method thereof | 江苏帆博生物制品有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-114213544-A | Heterophilic antibody blocking agent HBR-7 and preparation method thereof | 江苏帆博生物制品有限公司 | 2022-03-22 | — | — | CN | disclosed |