SCHEMBL30974584

SCHEMBL30974584

Cc1cccc(Oc2ccc(Cl)cc2C(N)=O)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.63
BRD4 O60885 1/20 0.47
MRGPRX4 Q96LA9 1/20 0.47
ALDH1A1 P00352 3/20 0.47
GAA P10253 2/20 0.47
HTR2C P28335 1/20 0.46
HTR2B P41595 1/20 0.46
PTGER4 P35408 2/20 0.46
CTNNB1 P35222 1/20 0.45
MAPT P10636 2/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
P2RX4 Q99571 1/20 0.43
NPC1 O15118 1/20 0.43
PKM P14618 1/20 0.43
HPGD P15428 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
KDM4E B2RXH2 1/20 0.43
GLA P06280 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29250434 1.00 L3MBTL1 (0.63) L3MBTL1BRD4MRGPRX4ALDH1A1GAA
SCHEMBL29250431 0.88 ALDH1A1 (0.51) L3MBTL1BRD4ALDH1A1GAACTNNB1
SCHEMBL8274395 0.88 PTGER4 (0.52) L3MBTL1BRD4MRGPRX4ALDH1A1GAA
SCHEMBL30974591 0.88 ALDH1A1 (0.51) L3MBTL1BRD4ALDH1A1GAACTNNB1
SCHEMBL5363217 0.87 L3MBTL1 (0.61) L3MBTL1MRGPRX4ALDH1A1GAAHTR2C
SCHEMBL30974620 0.85 L3MBTL1 (0.58) L3MBTL1MRGPRX4GAAHTR2CHTR2B
SCHEMBL5362837 0.85 L3MBTL1 (0.58) L3MBTL1MRGPRX4GAAHTR2CHTR2B
SCHEMBL12505384 0.84 STK39 (0.51) L3MBTL1BRD4MRGPRX4ALDH1A1GAA
SCHEMBL12505440 0.84 CTNNB1 (0.65) L3MBTL1BRD4MRGPRX4ALDH1A1GAA
SCHEMBL30974590 0.83 ALDH1A1 (0.50) L3MBTL1BRD4ALDH1A1GAACTNNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084706-A Synthesis method of 2- (4-hydroxyphenoxy) benzamide compound 河北科技大学 2024-05-28 CN disclosed