Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.40 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | F2R | P25116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16654345 | 0.79 | FAAH (0.56) | FAAHKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3097499 | 0.78 | FAAH (0.54) | FAAHKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7504454 | 0.75 | FAAH (0.52) | FAAHKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31019207 | 0.75 | FAAH (0.52) | FAAHKDM4EALDH1A1CYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL16825153 | 0.74 | FAAH (0.51) | FAAHKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL20515316 | 0.72 | HRH3 (0.41) | LMNA | |
| SCHEMBL5752037 | 0.70 | KDM4E (0.54) | KDM4EALDH1A1HTTHSD17B10 | |
| SCHEMBL19953764 | 0.68 | KDM1A (0.60) | FAAHKDM4ECYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL28456110 | 0.68 | KDM4E (0.48) | FAAHKDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4343778 | 0.68 | FAAH (0.45) | FAAHKDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180282280-A1 | QUINOLINE-BASED PROTEASOME INHIBITORS AND USES THEREOF | NATIONAL SCIENCE FOUNDATION | 2018-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180282280-A1 | QUINOLINE-BASED PROTEASOME INHIBITORS AND USES THEREOF | PSME1, PSMB1, PSME3 | FAAH 2203/4885KDM4E 1048/4885ALDH1A1 3556/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.