Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 5/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.34 |
| ▸ | CDK9 | P50750 | 4/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20588069 | 0.89 | HCAR3 (0.48) | HPGDHCAR3HCAR2MAPK14LPL | |
| SCHEMBL15332992 | 0.81 | SLC9A1 (0.42) | HCAR3LPLLIPGIRAK4IDO1 | |
| SCHEMBL29305746 | 0.80 | IRAK4 (0.43) | LPLLIPGIRAK4IDO1TDO2 | |
| SCHEMBL29608344 | 0.77 | SLC9A1 (0.41) | HPGDHCAR3LPLLIPGIRAK4 | |
| SCHEMBL26979177 | 0.76 | LPL (0.38) | LPLLIPGIRAK4IDO1TDO2 | |
| SCHEMBL30725371 | 0.76 | LPL (0.38) | LPLLIPGIRAK4IDO1TDO2 | |
| SCHEMBL793442 | 0.76 | LIPG (0.41) | LPLLIPGIRAK4IDO1TDO2 | |
| SCHEMBL30381461 | 0.75 | IRAK4 (0.56) | LPLLIPGIRAK4IDO1TDO2 | |
| SCHEMBL15661832 | 0.75 | IRAK4 (0.56) | LPLLIPGIRAK4IDO1TDO2 | |
| SCHEMBL30847373 | 0.75 | IRAK4 (0.39) | HPGDHCAR3LPLLIPGIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148210-A1 | CYCLIN-DEPENDENT KINASE 12 MODULATORS AND THERAPEUTIC USES THEREOF | ALLIANTHERA (SUZHOU) BIOPHARMACEUTICAL CO., LTD. (CN) | 2024-07-11 | — | — | WO | disclosed |