Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 8/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853887 | 0.80 | TLR8 (0.42) | GAAMAPTDDB1CRBNKDM4E | |
| SCHEMBL27249581 | 0.77 | ALDH1A1 (0.43) | GAAMAPTPIK3CBDDB1CRBN | |
| SCHEMBL26447071 | 0.76 | DPP4 (0.38) | GAAMAPTDDB1CRBNKDM4E | |
| SCHEMBL27249585 | 0.73 | LMNA (0.39) | MAPTSMN1; SMN2DDB1CRBNDPP4 | |
| SCHEMBL27249583 | 0.73 | DPP4 (0.43) | GAAMAPTSMN1; SMN2PIK3CBPIK3CD | |
| SCHEMBL23022464 | 0.72 | DDB1 (0.41) | GAADDB1CRBNKDM4EALDH1A1 | |
| SCHEMBL19848258 | 0.72 | DDB1 (0.41) | GAADDB1CRBNKDM4EALDH1A1 | |
| SCHEMBL30976952 | 0.72 | CTSS (0.36) | BACE1 | |
| SCHEMBL29435809 | 0.72 | DDB1 (0.41) | GAADDB1CRBNKDM4EALDH1A1 | |
| SCHEMBL31140536 | 0.71 | RAB9A (0.35) | KDM4EBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688144-A1 | COMPOUNDS AS GLP-1R AGONISTS | Terns Pharmaceuticals, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| WO-2024206878-A1 | COMPOUNDS AS GLP-1R AGONISTS | TERNS PHARMACEUTICALS, INC. (US) | 2024-10-03 | — | — | WO | disclosed |