Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | CTSS | P25774 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30977182 | 1.00 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL22451614 | 0.95 | CYP1A2 (0.52) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL8065326 | 0.92 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL13405298 | 0.92 | CYP1A2 (0.49) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL28286746 | 0.86 | ITGB3 (0.47) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL28286745 | 0.86 | ITGB3 (0.47) | CYP1A2CYP2C9CYP2C19HTTCTSK | |
| SCHEMBL31498517 | 0.85 | CTSS (0.46) | KMT2ACTSKCTSSTSHRHDAC4 | |
| SCHEMBL646731 | 0.83 | CYP1A2 (0.59) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL24692237 | 0.82 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 | |
| SCHEMBL2721300 | 0.82 | CYP1A2 (0.68) | CYP1A2CYP2C9CYP2C19HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4640684-A1 | KRAS G12D INHIBITORS AND USES THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024131827-A1 | KRAS G12D INHIBITORS AND USES THEREOF | 上海和誉生物医药科技有限公司 | 2024-06-27 | — | — | WO | disclosed |