Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSK | P43235 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20835667 | 0.93 | CTSK (0.49) | CTSSCTSKPPARAPPARGTSHR | |
| SCHEMBL20835669 | 0.93 | CTSK (0.49) | CTSSCTSKPPARAPPARGTSHR | |
| SCHEMBL3621626 | 0.92 | HDAC4 (0.46) | CTSSCTSKKMT2ATSHRHDAC4 | |
| SCHEMBL30977182 | 0.85 | CYP1A2 (0.54) | CTSSCTSKKMT2ATSHRHDAC4 | |
| SCHEMBL30977183 | 0.85 | CYP1A2 (0.54) | CTSSCTSKKMT2ATSHRHDAC4 | |
| SCHEMBL1324835 | 0.82 | FOLH1 (0.56) | CTSSCTSKPPARAPPARGACE | |
| SCHEMBL2769978 | 0.82 | FOLH1 (0.56) | CTSSCTSKPPARAPPARGACE | |
| SCHEMBL1318658 | 0.82 | FOLH1 (0.56) | CTSSCTSKPPARAPPARGACE | |
| SCHEMBL28286745 | 0.81 | ITGB3 (0.47) | CTSSCTSKHDAC4HDAC1HDAC6 | |
| SCHEMBL28286746 | 0.81 | ITGB3 (0.47) | CTSSCTSKHDAC4HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119894891-A | KRAS G12D inhibitor and application thereof | 上海和誉生物医药科技有限公司 | 2025-04-25 | — | — | CN | disclosed |