Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.41 |
| ▸ | MPL | P40238 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL756255 | 0.86 | PTPN7 (0.50) | HTR2ASLC6A4KCNH2PTPN7DUSP3 | |
| SCHEMBL29775423 | 0.86 | PTPN7 (0.50) | HTR2ASLC6A4KCNH2PTPN7DUSP3 | |
| SCHEMBL6764131 | 0.76 | HTR2A (0.43) | HTR2ASLC6A4KCNH2PTPN7DUSP3 | |
| SCHEMBL6832255 | 0.74 | NQO1 (0.46) | HTR2ASLC6A4KCNH2PTPN7DUSP3 | |
| SCHEMBL12896068 | 0.74 | SLC6A4 (0.43) | HTR2ASLC6A4KCNH2AR | |
| SCHEMBL29939130 | 0.72 | KIF11 (0.40) | PTPN7DUSP3 | |
| SCHEMBL17352133 | 0.71 | ALDH1A1 (0.53) | HTR2ASLC6A4KCNH2AR | |
| SCHEMBL1893249 | 0.71 | LMNA (0.44) | HTR2ASLC6A4KCNH2AREPHX2 | |
| SCHEMBL21271958 | 0.71 | MRGPRX4 (0.38) | SLC6A4 | |
| SCHEMBL15305003 | 0.71 | CYP11B2 (0.59) | CYP11B1CYP11B2AREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4619402-A1 | GPR17 MODULATORS AND USES THEREOF | Myrobalan Therapeutics, Inc. (US) | 2025-09-24 | — | — | EP | disclosed |
| CN-119613397-A | N-heteroaromatic ring-3-sulfonamide compounds and use thereof for preparing GPR17 receptor inhibitors | 迈巴制药(南京)有限公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2024104462-A1 | GPR17 MODULATORS AND USES THEREOF | MYROBALAN THERAPEUTICS NANJING CO. LTD (CN) | 2024-05-23 | — | — | WO | disclosed |