SCHEMBL30979262

SCHEMBL30979262

COc1cc(O)cc(Cc2ccccc2)c1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.63
GABRG2 P18507 1/20 0.63
GABRB3 P28472 1/20 0.63
GABRA3 P34903 1/20 0.63
GABRA2 P47869 1/20 0.63
GABRB2 P47870 1/20 0.63
LTA4H P09960 1/20 0.58
CALM1 P0DP23 7/20 0.57
KDM4E B2RXH2 1/20 0.53
MEN1 O00255 1/20 0.53
USP2 O75604 1/20 0.53
ALDH1A1 P00352 1/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
MAPT P10636 1/20 0.53
HPGD P15428 1/20 0.53
KMT2A Q03164 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
TRPV1 Q8NER1 1/20 0.53
HSD17B10 Q99714 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29215244 1.00 GABRA1 (0.63) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL11810459 0.87 LTA4H (0.69) LTA4HCALM1MEN1ALDH1A1KMT2A
SCHEMBL11504762 0.86 GABRA1 (0.78) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL7521964 0.80 CALM1 (0.60) LTA4HCALM1PTPN1IDH1BRD4
SCHEMBL5791635 0.79 MAOB (0.69) GABRA1GABRG2GABRB3GABRA3GABRA2
Batatasin Iii SCHEMBL29629601 0.77 GABRA1 (1.00) GABRA1GABRG2GABRB3GABRA3GABRA2
Batatasin Iii SCHEMBL29352616 0.77 GABRA1 (1.00) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL30574244 0.77 GABRA1 (0.87) GABRA1GABRG2GABRB3GABRA3GABRA2
Batatasin Iii SCHEMBL11505373 0.77 GABRA1 (1.00) GABRA1GABRG2GABRB3GABRA3GABRA2
SCHEMBL2092574 0.77 LTA4H (0.67) LTA4HCALM1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118076767-A Method and formulation for producing an optical metal oxide layer 默克专利有限公司 2024-05-24 CN disclosed