Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 6/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30979900 | 0.72 | KDM4E (0.32) | EGFR | |
| SCHEMBL5039456 | 0.69 | MGLL (0.39) | MGLL | |
| SCHEMBL27389897 | 0.68 | IP6K1 (0.53) | EGFRPIK3CAPIK3CDCHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL20958774 | 0.68 | ALDH1A1 (0.45) | CHRNB2CHRNA7CHRNA4ACHE | |
| Hydrochloric Acid SCHEMBL20703272 | 0.68 | ALDH1A1 (0.45) | CHRNB2CHRNA7CHRNA4ACHE | |
| SCHEMBL12182488 | 0.67 | CHRNA7 (0.68) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL8870802 | 0.67 | MAP4K4 (0.54) | EGFRPIK3CAPIK3CDPSMB5 | |
| SCHEMBL2509355 | 0.66 | TRPA1 (0.47) | — | |
| SCHEMBL30241134 | 0.65 | EGFR (0.50) | EGFRBACE1PSMB5 | |
| SCHEMBL30979882 | 0.65 | EGFR (0.58) | EGFRPIK3CAPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246940-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | VORONOI INC. (KR) | 2024-07-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246940-A1 | HETEROARYL DERIVATIVE COMPOUND AND USE THEREOF | ERBB2, EGFR, ERBB3 | EGFR 2/4885PIK3CA 112/4885PIK3CD 133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.