SCHEMBL30980602

SCHEMBL30980602

CC(CCCNC(=O)n1ccnc1)(CCCNC(=O)n1ccnc1)NC(=O)NCCOCCOCCOCCNC(=O)OCc1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HTT P42858 1/20 0.40
GHSR Q92847 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MAPT P10636 2/20 0.38
TGM2 P21980 1/20 0.37
ANPEP P15144 1/20 0.37
KEAP1 Q14145 3/20 0.37
NFE2L2 Q16236 3/20 0.37
DPP8 Q6V1X1 1/20 0.36
DPP7 Q9UHL4 1/20 0.36
FOLH1 Q04609 1/20 0.35
HRH4 Q9H3N8 1/20 0.35
CYP26A1 O43174 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30980576 0.87 LMNA (0.64) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL30980762 0.82 LMNA (0.58) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL30980695 0.80 LMNA (0.60) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL30980778 0.80 HTT (0.44) LMNASMN1; SMN2HTTTGM2ANPEP
SCHEMBL31078952 0.77 SMN1; SMN2 (0.42) LMNASMN1; SMN2HTTGHSRL3MBTL1
SCHEMBL3225482 0.77 SMN1; SMN2 (0.50) LMNASMN1; SMN2HTTHRH4
SCHEMBL7466451 0.73 HTT (0.61) LMNASMN1; SMN2HTTTGM2ANPEP
SCHEMBL20393801 0.71 TDP1 (0.38) L3MBTL1
SCHEMBL30823376 0.71 SMN1; SMN2 (0.97) LMNASMN1; SMN2HTTL3MBTL1MAPT
SCHEMBL7372302 0.69 SMN1; SMN2 (1.00) LMNASMN1; SMN2HTTL3MBTL1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651902-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
EP-4651901-A1 CYCLING LYSOSOMAL TARGETING ANTIBODY CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
WO-2025035040-A1 LYSOSOMAL TARGETING BIFUNCTIONAL MOLECULES FOR DEGRADATION OF MUSCLE-SPECIFIC KINASE AUTOANTIBODIES LYCIA THERAPEUTICS, INC. (US) 2025-02-13 WO disclosed
WO-2024155747-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed