Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30980778 | 0.88 | HTT (0.44) | SMN1; SMN2LMNAHTTHRH4POLB | |
| SCHEMBL30980576 | 0.81 | LMNA (0.64) | SMN1; SMN2LMNAHTTHRH4POLB | |
| SCHEMBL3225482 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHTTHRH4CYP19A1 | |
| SCHEMBL30980602 | 0.77 | LMNA (0.48) | SMN1; SMN2LMNAHTTHRH4TGM2 | |
| SCHEMBL12108559 | 0.77 | MAPT (0.52) | SMN1; SMN2LMNAHTTPOLBTGM2 | |
| SCHEMBL30980799 | 0.74 | LMNA (0.49) | SMN1; SMN2LMNAHTTCTSS | |
| SCHEMBL19767522 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHTTPOLBTGM2 | |
| SCHEMBL31749309 | 0.74 | LMNA (0.48) | SMN1; SMN2LMNAHTTTGM2L3MBTL1 | |
| SCHEMBL7466451 | 0.74 | HTT (0.61) | SMN1; SMN2LMNAHTTHRH4POLB | |
| SCHEMBL5859633 | 0.74 | NAMPT (0.53) | SMN1; SMN2POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4651904-A1 | LYSOSOMAL TARGETING BIFUNCTIONAL MOLECULES FOR DEGRADATION OF AUTOANTIBODIES | Lycia Therapeutics, Inc. (US) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155750-A1 | LYSOSOMAL TARGETING BIFUNCTIONAL MOLECULES FOR DEGRADATION OF AUTOANTIBODIES | LYCIA THERAPEUTICS, INC. (US) | 2024-07-25 | — | — | WO | disclosed |