Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100634 | 1.00 | LMNA (0.50) | LMNAFOLH1ENPEPKDM4CKDM4A | |
| SCHEMBL570879 | 1.00 | LMNA (0.50) | LMNAFOLH1ENPEPKDM4CKDM4A | |
| SCHEMBL4610335 | 1.00 | LMNA (0.50) | LMNAFOLH1ENPEPKDM4CKDM4A | |
| SCHEMBL2789794 | 1.00 | LMNA (0.50) | LMNAFOLH1ENPEPKDM4CKDM4A | |
| SCHEMBL4610383 | 1.00 | LMNA (0.50) | LMNAFOLH1ENPEPKDM4CKDM4A | |
| SCHEMBL4610376 | 1.00 | LMNA (0.50) | LMNAFOLH1ENPEPKDM4CKDM4A | |
| SCHEMBL472270 | 1.00 | — | — | |
| SCHEMBL4608683 | 1.00 | LMNA (0.50) | LMNAFOLH1ENPEPKDM4CKDM4A | |
| SCHEMBL4611128 | 1.00 | LMNA (0.50) | LMNAFOLH1ENPEPKDM4CKDM4A | |
| SCHEMBL4609708 | 1.00 | LMNA (0.50) | LMNAFOLH1ENPEPKDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209008-A1 | METHOD FOR PRODUCING ASYMMETRIC PHOSPHORIC ACID TRIESTER, METHOD FOR PRODUCING SYMMETRIC PHOSPHORIC ACID TRIESTER, METHOD FOR PRODUCING PHOSPHORIC ACID ESTER, AND METHOD FOR PRODUCING ORGANOPHOSPHORUS COMPOUND | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2024-06-27 | — | — | US | disclosed |
| EP-4303222-A1 | METHOD FOR PRODUCING ASYMMETRIC PHOSPHORIC ACID TRIESTER, METHOD FOR PRODUCING SYMMETRIC PHOSPHORIC ACID TRIESTER, METHOD FOR PRODUCING PHOSPHORIC ACID ESTER, AND METHOD FOR PRODUCING ORGANOPHOSPHORUS COMPOUND | Tokyo Institute of Technology (JP) | 2024-01-10 | — | — | EP | disclosed |
| US-11819822-B2 | Silica composite monolith as a solid phase extraction material | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2023-11-21 | — | — | US | disclosed |
| CN-116917301-A | Method for producing asymmetric phosphotriester, method for producing symmetric phosphotriester, method for producing phosphate, and method for producing organic phosphorus compound | 国立大学法人东京工业大学 | 2023-10-20 | — | — | CN | disclosed |
| CN-109071960-B | Silicon-containing heterocyclic matting agents, compounds and polymers | 富士胶片和光纯药株式会社 | 2021-01-12 | — | — | CN | disclosed |
| US-20200246778-A1 | SILICA COMPOSITE MONOLITH AS A SOLID PHASE EXTRACTION MATERIAL | UNIV ALBERTA (CA) | 2020-08-06 | — | — | US | disclosed |
| CN-111218126-A | Matting agent, compound and polymer | 富士胶片和光纯药株式会社 | 2020-06-02 | — | — | CN | disclosed |
| US-20150081018-A1 | METHODS AND SUBSTRATES FOR DIFFERENTIATION OF NEURAL STEM CELLS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2015-03-19 | — | — | US | disclosed |
| US-20100279963-A1 | DICARBONYL DERIVATIVES AND METHODS OF USE | ABRAXIS BIOSCIENCE, LLC (US) | 2010-11-04 | — | — | US | disclosed |
| US-7799954-B2 | Dicarbonyl derivatives and methods of use | ABRAXIS BIOSCIENCE, LLC (US) | 2010-09-21 | — | — | US | disclosed |
| EP-2125694-A2 | DICARBONYL DERIVATIVES AND METHODS OF USE | Abraxis BioScience, Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| EP-1976505-A1 | COMBRETASTATIN DERIVATIVES AND RELATED THERAPEUTIC METHODS | Abraxis BioScience, Inc. (US) | 2008-10-08 | — | — | EP | disclosed |
| US-20080146586-A1 | DICARBONYL DERIVATIVES AND METHODS OF USE | ABRAXIS BIOSCIENCE (US) | 2008-06-19 | — | — | US | disclosed |
| WO-2008064060-A2 | DICARBONYL DERIVATIVES AND METHODS OF USE | ABRAXIS BIOSCIENCE, INC. (US) | 2008-05-29 | — | — | WO | disclosed |
| WO-2007059118-A1 | COMBRETASTATIN DERIVATIVES AND RELATED THERAPEUTIC METHODS | ABRAXIS BIOSCIENCE, INC. (US) | 2007-05-24 | — | — | WO | disclosed |
| US-5650430-A | Radicicol derivatives, their preparation and their anti-tumor activity | SANKYO COMPANY, LIMITED (JP) | 1997-07-22 | — | — | US | disclosed |
| US-5597846-A | ESTERS OF RADICICOL | SANKYO COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | disclosed |
| WO-1991018905-A1 | RADICICOL DERIVATIVES, THEIR PREPARATION AND THEIR ANTI-TUMOR ACTIVITY | SANKYO COMPANY LIMITED (JP) | 1991-12-12 | — | — | WO | disclosed |
| EP-0460950-A1 | Radicicol derivatives, their preparation and their anti-tumour activity | Sankyo Company Limited (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4419254-A | POLYSILOXANE, THICKENER, ALIPHATIC MERCAPTAN | TOSHIBA SILICONES LIMITED (US) | 1983-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146586-A1 | DICARBONYL DERIVATIVES AND METHODS OF USE | AADAC, DCK, MLYCD | LMNA 2382/4885FOLH1 893/4885ENPEP 1638/4885 |
| US-20100279963-A1 | DICARBONYL DERIVATIVES AND METHODS OF USE | AADAC, DCK, MLYCD | LMNA 2382/4885FOLH1 893/4885ENPEP 1638/4885 |
| US-20240209008-A1 | METHOD FOR PRODUCING ASYMMETRIC PHOSPHORIC ACID TRIESTER, METHOD FOR PRODUCING SYMMETRIC PHOSPHORIC ACID TRIESTER, METHOD FOR PRODUCING PHOSPHORIC ACID ESTER, AND METHOD FOR PRODUCING ORGANOPHOSPHORUS COMPOUND | HAO2, PLCB1, PHPT1 | LMNA 4235/4885FOLH1 3494/4885ENPEP 3924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.