Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.50 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.50 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 6/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30135921 | 0.89 | ALDH1A1 (0.54) | ITGB3ITGA2BALDH1A1GAACTSL | |
| SCHEMBL30136050 | 0.85 | ALDH1A1 (0.52) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL30965540 | 0.85 | DRD2 (0.58) | ITGB3ITGA2BALDH1A1GAACTSL | |
| SCHEMBL30136006 | 0.83 | TSHR (0.60) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL7617 | 0.82 | ALDH1A1 (0.70) | ITGB3ITGA2BALDH1A1GAACTSL | |
| Hydrochloric Acid SCHEMBL605486 | 0.81 | ALDH1A1 (0.68) | ITGB3ITGA2BALDH1A1GAACTSL | |
| SCHEMBL31334311 | 0.80 | ALDH1A1 (0.58) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL1870932 | 0.79 | ALDH1A1 (0.67) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL30981171 | 0.79 | ALDH1A1 (0.54) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL30135759 | 0.78 | SIGMAR1 (0.59) | ITGB3ITGA2BALDH1A1GAACTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4652161-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | Uppthera, Inc. (KR) | 2025-11-26 | — | — | EP | disclosed |
| WO-2024155112-A1 | 2,4-DIANILINOPYRIMIDINE-BASED AURORA-A KINASE SELECTIVE DEGRADATION INDUCING COMPOUNDS | UPPTHERA, INC. (KR) | 2024-07-25 | — | — | WO | disclosed |