Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | CTSL | P07711 | 1/20 | 0.64 |
| ▸ | CTSB | P07858 | 1/20 | 0.64 |
| ▸ | CTSK | P43235 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | DPP4 | P27487 | 7/20 | 0.61 |
| ▸ | DPP7 | Q9UHL4 | 7/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | TGM2 | P21980 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | F13A1 | P00488 | 1/20 | 0.53 |
| ▸ | TGM1 | P22735 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2551898 | 0.95 | DPP4 (0.62) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL31334638 | 0.93 | ALDH1A1 (0.58) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL13740409 | 0.92 | CTSL (0.68) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL3003867 | 0.92 | CTSL (0.68) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL3667335 | 0.92 | CTSL (0.68) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL854004 | 0.87 | ALDH1A1 (0.62) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL3948461 | 0.87 | ALDH1A1 (0.85) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL3948456 | 0.87 | ALDH1A1 (0.85) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL381922 | 0.87 | ALDH1A1 (0.85) | ALDH1A1GAACTSLCTSBCTSK | |
| SCHEMBL13402357 | 0.86 | ALDH1A1 (0.67) | ALDH1A1GAACTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |
| CN-107445976-A | Antimicrobe compound and its preparation and application | 梅琳塔治疗公司 | 2017-12-08 | — | — | CN | disclosed |
| CN-107266470-A | Antimicrobe compound and its preparation and application | 梅琳塔治疗公司 | 2017-10-20 | — | — | CN | disclosed |
| WO-2015161011-A1 | BENZAMIDE CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2015-10-22 | — | — | WO | disclosed |
| EP-2226322-B1 | IMIDAZOLE CARBONYL COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2015-01-21 | — | — | EP | disclosed |
| US-8927588-B2 | Imidazole carbonyl compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2015-01-06 | — | — | US | disclosed |
| US-20140073622-A1 | IMIDAZOLE CARBONYL COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2014-03-13 | — | — | US | disclosed |
| US-8536197-B2 | Imidazole carbonyl compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-09-17 | — | — | US | disclosed |
| US-8476301-B2 | Pyrrolidin-3-ylacetic acid derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-07-02 | — | — | US | disclosed |
| US-20130065925-A1 | PYRROLIDIN-3-YLACETIC ACID DERIVATIVE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2013-03-14 | — | — | US | disclosed |
| CN-102712657-A | Antimicrobial compounds and methods of making and using the same | RIB X PHARMACEUTICALS INC | 2012-10-03 | — | — | CN | disclosed |
| WO-2011060321-A1 | TRANSGLUTAMINASE TG2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | CHDI, INC. (US) | 2011-05-19 | — | — | WO | disclosed |
| US-20100311966-A1 | IMIDAZOLE CARBONYL COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-12-09 | — | — | US | disclosed |
| EP-2226322-A1 | IMIDAZOLE CARBONYL COMPOUND | Daiichi Sankyo Company, Limited (JP) | 2010-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100311966-A1 | IMIDAZOLE CARBONYL COMPOUND | TOP1, TOP2B, TOP2A | ALDH1A1 3596/4885GAA 1609/4885CTSL 1737/4885 |
| US-20130065925-A1 | PYRROLIDIN-3-YLACETIC ACID DERIVATIVE | CX3CR1, CCR2, CCL2 | ALDH1A1 1418/4885GAA 3637/4885CTSL 1463/4885 |
| US-20140073622-A1 | IMIDAZOLE CARBONYL COMPOUND | TOP1, TOP2B, TOP2A | ALDH1A1 1220/4885GAA 1089/4885CTSL 1294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.