Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.31 |
| ▸ | QPCT | Q16769 | 1/20 | 0.31 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.30 |
| ▸ | ULK1 | O75385 | 1/20 | 0.30 |
| ▸ | ULK2 | Q8IYT8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4144530 | 0.94 | CDK1 (0.38) | FLT3CDK1PAK1LRRK2 | |
| SCHEMBL30983864 | 0.71 | — | — | |
| SCHEMBL7626864 | 0.69 | ALDH1A1 (0.34) | QPCTQPCTL | |
| SCHEMBL4163924 | 0.69 | CNR2 (0.35) | QPCTQPCTL | |
| SCHEMBL30984078 | 0.68 | — | — | |
| SCHEMBL2789819 | 0.68 | PAK1 (0.51) | FLT3PAK1ULK1ULK2 | |
| SCHEMBL5440110 | 0.67 | CYP1A2 (0.48) | CDK1 | |
| SCHEMBL7662487 | 0.66 | PAK1 (0.60) | FLT3CDK1PAK1ULK1 | |
| SCHEMBL1551868 | 0.66 | PAK1 (0.56) | FLT3PAK1ULK1ULK2 | |
| SCHEMBL9854783 | 0.66 | MAPK8 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630410-A1 | POLQ INHIBITORS | Astrazeneca AB (SE) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024121753-A1 | POLQ INHIBITORS | ASTRAZENECA AB (SE) | 2024-06-13 | — | — | WO | disclosed |