SCHEMBL3098531

SCHEMBL3098531

O=[N+]([O-])N1C=Cc2ccccc2O1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
CASP6 P55212 1/20 0.34
KMT2A Q03164 1/20 0.34
P2RY6 Q15077 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL6413526 0.95 MEN1 (0.35) MEN1POLBCASP6KMT2AP2RY6
SCHEMBL1491181 0.67 KDM4E (0.33) MEN1KMT2A
SCHEMBL5494922 0.67 KDM4E (0.33) MEN1KMT2A
SCHEMBL22115886 0.67 KDM4E (0.33) MEN1KMT2A
SCHEMBL3235007 0.67 KDM4E (0.33) MEN1KMT2A
SCHEMBL1661412 0.67 BRD4 (0.34) MEN1KMT2A
SCHEMBL3342528 0.67 KDM4E (0.37) MEN1KMT2A
SCHEMBL7383136 0.67 HTR2C (0.31) MEN1KMT2A
SCHEMBL17923825 0.66 LMNA (0.37) MEN1KMT2AP2RY6
Ammonia Solution, Strong SCHEMBL27779538 0.66 BRD4 (0.33) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118704272-A Flame-retardant archival product paper and preparation method thereof 河北墨达纸业有限公司 2024-09-27 CN claimed
EP-1212330-B1 ANDROGEN RECEPTOR MODULATOR COMPOUNDS AND METHODS LIGAND PHARM INC (US) 2006-04-19 EP claimed
EP-0103797-B1 SUBSTITUTED BENZOXAZINE DERIVATIVES BAYER AG (DE) 1986-11-26 EP claimed
JP-61140571-A None JP disclosed
CN-118704272-A Flame-retardant archival product paper and preparation method thereof 河北墨达纸业有限公司 2024-09-27 CN disclosed
US-7799913-B2 Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses CORTEX PHARMACEUTICALS, INC. (US) 2010-09-21 US disclosed
US-20080300241-A9 Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods HIGUCHI ROBERT I 2008-12-04 US disclosed
US-7214690-B2 Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED (US) 2007-05-08 US disclosed
US-20070072849-A1 Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods LIGAND PHARMACEUTICALS INCORPORATED 2007-03-29 US disclosed
US-6919334-B2 Antidepressant azaheterocyclymethyl derivatives of 4,5-dihydroimidazo[1,4,5-de][1,4]benzoxazine WYETH (US) 2005-07-19 US disclosed
CN-1620440-A Carbonylbenzoxazine compounds for enhancing glutamatergic synaptic responses CORTEX PHARMA INC (US) 2005-05-25 CN disclosed
US-5118323-A Hair dyes CLAIROL, INC. 1992-06-02 US disclosed
EP-0199543-B1 HETEROCYCLIC AMIDE DERIVATIVES ICI AMERICAS INC. (US) 1991-12-04 EP disclosed
US-5055110-A Hair dyes CLAIROL INCORPORATED (US) 1991-10-08 US disclosed
US-5030643-A Antiallergens, antiinflammatory agents ICI AMERICAS INC. (US) 1991-07-09 US disclosed
WO-1991007394-A1 BENZOXAZINE DYES BRISTOL-MYERS SQUIBB COMPANY (US) 1991-05-30 WO disclosed
US-4859692-A Heterocyclic amide derivatives and pharmaceutical use ICI AMERICAS INC. (US) 1989-08-22 US disclosed
EP-0199543-A2 Heterocyclic amide derivatives ICI AMERICAS INC. (US) 1986-10-29 EP disclosed
JP-S61140571-A NITROBENZOXAZINE DERIVATIVE, AND PREPARATION THEREOF SUMITOMO CHEM CO LTD 1986-06-27 JP disclosed
US-4537888-A Substituted benzoxazine derivatives and fungicidal use BAYER AKTIENGESELLSCHAFT (DE) 1985-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080300241-A9 Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods AR, NR5A1, FSHR MEN1 2402/4885POLB 2317/4885CASP6 4633/4885
US-20070072849-A1 Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods AR, NR5A1, FSHR MEN1 2402/4885POLB 2317/4885CASP6 4633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.