Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SCD | O00767 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31461158 | 0.98 | KDM4E (0.58) | USP2KDM4EALOX15HSD17B10RAB9A | |
| SCHEMBL31461172 | 0.85 | LMNA (0.67) | USP2KDM4EALOX15HSD17B10RAB9A | |
| SCHEMBL15219368 | 0.85 | MAPT (0.50) | USP2KDM4EALOX15HSD17B10RAB9A | |
| SCHEMBL10253559 | 0.80 | CNR2 (0.76) | RAB9ASMN1; SMN2LMNA | |
| SCHEMBL9370348 | 0.77 | LMNA (0.61) | USP2KDM4EHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL9371263 | 0.76 | NPC1 (0.68) | USP2KDM4EHSD17B10RAB9ASMN1; SMN2 | |
| SCHEMBL10816647 | 0.75 | RAB9A (0.71) | KDM4EHSD17B10RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1691061 | 0.75 | MAPT (0.68) | KDM4EHSD17B10RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9370411 | 0.74 | ACHE (0.67) | KDM4EHSD17B10RAB9ASMN1; SMN2MAPT | |
| SCHEMBL25769829 | 0.74 | MAPT (0.70) | USP2KDM4EALOX15HSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4400172-A2 | PIPERIDIN-4-YL AZETIDINE DERIVATIVES AS JAK1 INHIBITORS | Incyte Holdings Corporation (US) | 2024-07-17 | — | — | EP | disclosed |