Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7388659 | 0.98 | MEN1 (0.54) | MEN1KMT2ALMNAHTTUSP2 | |
| SCHEMBL15922927 | 0.98 | MEN1 (0.54) | MEN1KMT2ALMNAHTTUSP2 | |
| SCHEMBL6750345 | 0.98 | MEN1 (0.54) | MEN1KMT2ALMNAHTTUSP2 | |
| SCHEMBL27517121 | 0.94 | MEN1 (0.49) | MEN1KMT2ALMNAHTTUSP2 | |
| SCHEMBL1427333 | 0.93 | DRD2 (0.50) | MEN1KMT2ALMNAHTTUSP2 | |
| SCHEMBL11615899 | 0.89 | KCNA3 (0.55) | HRH3DRD3L3MBTL1CYP2D6GAA | |
| SCHEMBL10338308 | 0.89 | MEN1 (0.60) | MEN1KMT2ALMNAHTTUSP2 | |
| SCHEMBL27515741 | 0.88 | MEN1 (0.46) | MEN1KMT2ALMNAHTTUSP2 | |
| SCHEMBL118043 | 0.86 | CYP1A2 (0.50) | MEN1KMT2ALMNAHTTUSP2 | |
| SCHEMBL9361193 | 0.86 | LSS (0.59) | LMNAHRH3KDM4ESMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217552-A1 | 2-(TERT-BUTYL)-4-METHYLPHENYL APPENDED 1,4-DIAZEPANE BASED NOVEL TFEB ACTIVATING COMPOUNDS AS AUTOPHAGY MODULATORS FOR NEURODEGENERATIVE DISORDERS INCLUDING ALZHEIMER'S DISEASE (AD) | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2025-10-16 | — | — | WO | disclosed |
| CN-108440278-B | Dicarboxy chalcone compound and its application in preparing anti-inflammatory medicine | 中国计量大学 | 2021-01-12 | — | — | CN | disclosed |
| CN-102617494-B | Triazole compound containing vinyl ether structure and preparation method and application thereof | NANJING TECH UNIVERSITY (CN) | 2014-10-29 | — | — | CN | disclosed |
| EP-2726457-A1 | INDOLEAMINE DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES | Adamed sp. z o.o. (PL) | 2014-05-07 | — | — | EP | disclosed |
| US-20140121216-A1 | INDOLEAMINE DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES | ADAMED SP. Z O.O. (PL) | 2014-05-01 | — | — | US | disclosed |
| CN-103649048-A | Indoleamine derivatives for the treatment of central nervous system diseases | ADAMED SP ZOO | 2014-03-19 | — | — | CN | disclosed |
| US-8367702-B2 | Quinolone derivative | ASTELLAS PHARMA INC. (JP) | 2013-02-05 | — | — | US | disclosed |
| WO-2013001499-A1 | INDOLEAMINE DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES | ADAMED SP. Z O.O. (PL) | 2013-01-03 | — | — | WO | disclosed |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2010-10-07 | — | — | US | disclosed |
| CN-101801933-A | quinolone derivative | ASTELLAS PHARMA INC | 2010-08-11 | — | — | CN | disclosed |
| EP-0527079-B1 | N-(isoquinolein-5-yl)-sulfonyl azacycloalkanes, their process of preparation and pharmaceutical compositions containing them | ADIR (FR) | 1996-10-23 | — | — | EP | disclosed |
| WO-1996012718-A1 | NOUVELLES 2-[1-(φ-PHENOXYALCOYLPIPERIDIN-4-YL)AMINOMETHYLENE]-2H-BENZOFURAN-3-ONES SUBSTITUEES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE | PIERRE FABRE MEDICAMENT (FR) | 1996-05-02 | — | — | WO | disclosed |
| EP-0672031-A1 | CATECHOL DIETHERS AS SELECTIVE PDE IV? INHIBITORS | PFIZER INC. (US) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994012461-A1 | CATECHOL DIETHERS AS SELECTIVE PDEIV INHIBITORS | PFIZER INC. (US) | 1994-06-09 | — | — | WO | disclosed |
| US-5298503-A | Cardiovascular | ADIR ET COMPAGNIE (FR) | 1994-03-29 | — | — | US | disclosed |
| US-5208243-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-05-04 | — | — | US | disclosed |
| EP-0527079-A1 | N-(isoquinolein-5-yl)-sulfonyl azacycloalkanes, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-02-10 | — | — | EP | disclosed |
| EP-0526342-A1 | Isoquinolin-5yl-sulphonamides, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1993-02-03 | — | — | EP | disclosed |
| US-4139620-A | HYPOTENSIVE AGENTS | A. H. ROBINS COMPANY, INC. (US) | 1979-02-13 | — | — | US | disclosed |
| US-4096331-A | HYPOTENSIVE | A. H. ROBINS COMPANY, INCORPORATED (US) | 1978-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140121216-A1 | INDOLEAMINE DERIVATIVES FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISEASES | TPH1, TPH2, HTR3A | MEN1 361/4885KMT2A 1540/4885LMNA 1729/4885 |
| US-20100256113-A1 | QUINOLONE DERIVATIVE | NQO1, NQO2, NADK | MEN1 4763/4885KMT2A 1299/4885LMNA 2595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.