Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3087428 | 0.87 | CA12 (0.37) | ALDH1A1MAPK1USP2TP53ALOX15 | |
| SCHEMBL3087332 | 0.87 | METAP2 (0.33) | ALDH1A1CA2CA1KDM4ECA12 | |
| SCHEMBL3098722 | 0.84 | FPR2 (0.43) | MAPK1CA2CA1CA12CA9 | |
| SCHEMBL3090743 | 0.83 | NOS2 (0.37) | — | |
| SCHEMBL3090739 | 0.83 | NOS2 (0.37) | — | |
| SCHEMBL3091741 | 0.83 | PPARD (0.43) | ALDH1A1MAPK1CA2CA1KDM4E | |
| SCHEMBL3097954 | 0.82 | GGH (0.49) | — | |
| SCHEMBL3109219 | 0.82 | FPR2 (0.34) | MAPK1ALOX15CA2CA1KDM4E | |
| SCHEMBL2991039 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPK1USP2TP53ALOX15 | |
| SCHEMBL2991041 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPK1USP2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |