Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3270459 | 0.84 | NOTUM (0.57) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL30987380 | 0.82 | NOTUM (0.52) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL28664383 | 0.81 | DRD2 (0.47) | — | |
| SCHEMBL30987393 | 0.79 | ABCG2 (0.57) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL30987400 | 0.77 | STIM1 (0.52) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL18029589 | 0.77 | FLT3 (0.50) | CA1CA2 | |
| SCHEMBL30987381 | 0.76 | BCHE (0.62) | NOTUMCA12CA1CA2CA9 | |
| SCHEMBL20532909 | 0.76 | KDM1A (0.45) | — | |
| SCHEMBL20533135 | 0.76 | GRM5 (0.44) | — | |
| SCHEMBL23879988 | 0.75 | FLT3 (0.46) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | disclosed |