Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MIF | P14174 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3270459 | 0.88 | NOTUM (0.57) | NOTUMCA1CA2CA12CA9 | |
| SCHEMBL28319778 | 0.85 | FLT3 (0.67) | CA1CA2FLT3GSK3BCA5A | |
| SCHEMBL30987396 | 0.82 | NOTUM (0.49) | NOTUMCA1CA2CA12CA9 | |
| SCHEMBL30987390 | 0.80 | MIF (0.55) | NOTUMCA1CA2CA12CA9 | |
| SCHEMBL30987381 | 0.79 | BCHE (0.62) | NOTUMCA1CA2CA12CA9 | |
| SCHEMBL28639707 | 0.79 | FLT3 (0.49) | NOTUMCA1CA2FLT3GSK3B | |
| SCHEMBL30987376 | 0.78 | CA2 (0.51) | NOTUMCA1CA2CA12CA9 | |
| SCHEMBL18029589 | 0.77 | FLT3 (0.50) | CA1CA2FLT3GSK3BCA5A | |
| SCHEMBL23879988 | 0.76 | FLT3 (0.46) | CA1CA2FLT3GSK3BCA5A | |
| SCHEMBL16220810 | 0.75 | CA1 (0.68) | NOTUMCA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | claimed |
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | disclosed |