Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.57 |
| ▸ | MIF | P14174 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987400 | 0.87 | STIM1 (0.52) | ABCG2MIFSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30987390 | 0.85 | MIF (0.55) | ABCG2MIFNPC1RAB9AALDH1A1 | |
| SCHEMBL30987381 | 0.84 | BCHE (0.62) | ABCG2MIFNPC1ALDH1A1LMNA | |
| SCHEMBL25055359 | 0.82 | MIF (0.74) | ABCG2MIFNPC1MAPTALDH1A1 | |
| SCHEMBL30987377 | 0.82 | MIF (0.55) | ABCG2MIFNPC1ALDH1A1PTGS2 | |
| SCHEMBL30987396 | 0.79 | NOTUM (0.49) | NOTUMCA1CA2CA12CA9 | |
| SCHEMBL12420365 | 0.77 | PTGS2 (0.67) | ABCG2SMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL30987376 | 0.77 | CA2 (0.51) | MIFSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL3270459 | 0.76 | NOTUM (0.57) | MIFSMN1; SMN2NPC1MAPTALDH1A1 | |
| SCHEMBL27903094 | 0.75 | PTGS2 (0.76) | NPC1RAB9AMEN1KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024133292-A1 | NOVEL CCR8 ANTAGONISTS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2024-06-27 | — | — | WO | disclosed |