Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987490 | 0.81 | CYP11B2 (0.47) | TSHRATMHTR1AHTR7CYP2D6 | |
| SCHEMBL30987481 | 0.75 | CYP2D6 (0.50) | TSHRATMCYP2D6CYP2C19POLB | |
| SCHEMBL30987501 | 0.74 | ADRB2 (0.54) | TSHRATMCYP2D6HIF1AKMT2A | |
| SCHEMBL30987497 | 0.70 | KMT2A (0.52) | TSHRATMCYP2D6CYP2C19POLB | |
| SCHEMBL30987486 | 0.70 | KMT2A (0.52) | TSHRATMCYP2D6CYP2C19POLB | |
| SCHEMBL30987489 | 0.70 | KMT2A (0.52) | TSHRATMCYP2D6CYP2C19POLB | |
| SCHEMBL30987499 | 0.68 | KMT2A (0.46) | TSHRATMCYP2D6CYP2C19POLB | |
| SCHEMBL30987480 | 0.67 | DRD4 (0.46) | TSHRATMCYP2D6CYP2C19POLB | |
| SCHEMBL30987500 | 0.64 | HTT (0.43) | TSHRATMCYP2D6CYP2C19POLB | |
| SCHEMBL3060495 | 0.62 | HSF1 (0.60) | TSHRATMCYP2D6CYP2C19POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139842-A | Oximes and their use in the treatment of GBA related diseases | 泽拉丹麦有限公司 | 2024-06-04 | — | — | CN | disclosed |