Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30987501 | 0.83 | ADRB2 (0.54) | CYP2D6TSHRHIF1AATMPRMT5 | |
| SCHEMBL30987478 | 0.81 | TSHR (0.42) | CYP2D6TSHRHIF1AATMACE2 | |
| SCHEMBL30987481 | 0.79 | CYP2D6 (0.50) | CYP2D6TSHRHIF1AATMACE2 | |
| SCHEMBL30987476 | 0.72 | ADRB2 (0.53) | ATMKDM4EPRMT5WDR77 | |
| SCHEMBL30987489 | 0.71 | KMT2A (0.52) | CYP2D6TSHRHIF1AATMACE2 | |
| SCHEMBL30987486 | 0.71 | KMT2A (0.52) | CYP2D6TSHRHIF1AATMACE2 | |
| SCHEMBL30987497 | 0.71 | KMT2A (0.52) | CYP2D6TSHRHIF1AATMACE2 | |
| SCHEMBL30987480 | 0.71 | DRD4 (0.46) | CYP2D6TSHRHIF1AATMCYP2C19 | |
| SCHEMBL7965929 | 0.71 | HTR1A (0.62) | HTR1A | |
| SCHEMBL6342412 | 0.70 | GAA (0.54) | CYP2D6TSHRHIF1AATMACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118139842-A | Oximes and their use in the treatment of GBA related diseases | 泽拉丹麦有限公司 | 2024-06-04 | — | — | CN | disclosed |