SCHEMBL30989604

SCHEMBL30989604

COc1cc(Cl)nnc1C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.42
LMNA P02545 3/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
RAB9A P51151 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA7 P43166 3/20 0.40
CA9 Q16790 3/20 0.40
CA14 Q9ULX7 3/20 0.40
CA4 P22748 2/20 0.40
CA6 P23280 2/20 0.40
CA3 P07451 1/20 0.40
PKM P14618 1/20 0.40
CA5A P35218 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
KDM4E B2RXH2 3/20 0.40
HPGD P15428 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24587304 1.00 ALDH1A1 (0.42) ALDH1A1LMNALCKFYNRAB9A
SCHEMBL30632327 0.85 ALDH1A1 (0.42) ALDH1A1LMNALCKFYNRAB9A
SCHEMBL24542675 0.85 ALDH1A1 (0.42) ALDH1A1LMNALCKFYNRAB9A
SCHEMBL5886488 0.84 ALDH1A1 (0.44) ALDH1A1LMNARAB9AL3MBTL1KDM4E
SCHEMBL31590096 0.84 ALDH1A1 (0.44) ALDH1A1LMNARAB9AL3MBTL1KDM4E
SCHEMBL24542630 0.78 ALDH1A1 (0.36) ALDH1A1LMNARAB9AL3MBTL1KDM4E
SCHEMBL24975920 0.76 ALDH1A1 (0.38) ALDH1A1LMNARAB9AL3MBTL1KDM4E
SCHEMBL19283132 0.75 PKM (0.50) ALDH1A1LMNALCKFYNCA12
SCHEMBL474100 0.75 ALDH1A1 (0.46) ALDH1A1PKMKDM4EHTTKMO
SCHEMBL17141437 0.74 POLB (0.43) ALDH1A1LMNALCKFYNRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026086928-A1 SARM1 MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2026-04-30 WO disclosed
US-20260027095-A1 Compounds as Inhibitors of Macrophage Migration Inhibitory Factor and the Use Thereof NANJING IMMUNOPHAGE BIOTECH CO LTD (CN) 2026-01-29 US disclosed
EP-4642779-A1 COMPOUNDS AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND THE USE THEREOF Nanjing Immunophage Biotech Co., Ltd (CN) 2025-11-05 EP disclosed
WO-2024141004-A1 COMPOUNDS AS INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR AND THE USE THEREOF NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) 2024-07-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027095-A1 Compounds as Inhibitors of Macrophage Migration Inhibitory Factor and the Use Thereof MIF, MSR1, CCR2 ALDH1A1 1403/4885LMNA 2863/4885LCK 4079/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.