Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989919 | 0.85 | PIK3C3 (0.38) | MEN1KMT2ACES2CES1HDAC4 | |
| SCHEMBL30989878 | 0.85 | PIK3C3 (0.38) | MEN1KMT2ACES2CES1HDAC4 | |
| SCHEMBL30989872 | 0.83 | MEN1 (0.36) | MEN1KMT2ACES2CES1HDAC4 | |
| SCHEMBL30989874 | 0.83 | MEN1 (0.36) | MEN1KMT2ACES2CES1HDAC4 | |
| SCHEMBL30989928 | 0.73 | PIK3C3 (0.44) | CES2CES1TRPM8RIPK1 | |
| SCHEMBL30990011 | 0.73 | PIK3C3 (0.44) | CES2CES1TRPM8RIPK1 | |
| SCHEMBL25373799 | 0.71 | CES2 (0.46) | MEN1KMT2ACES2CES1KDM4E | |
| SCHEMBL12244178 | 0.71 | CES2 (0.42) | MEN1KMT2ACES2CES1ALDH1A1 | |
| SCHEMBL30989876 | 0.70 | RIPK1 (0.48) | MEN1KMT2AALDH1A1NPC1RIPK1 | |
| SCHEMBL26763699 | 0.70 | MC4R (0.42) | MEN1KMT2ACES2CES1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |