Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989781 | 0.85 | RIPK1 (0.46) | RIPK1MEN1KMT2AATMNLRP3 | |
| SCHEMBL30989870 | 0.82 | RIPK1 (0.43) | RIPK1MEN1KMT2AATMNLRP3 | |
| SCHEMBL30989882 | 0.75 | MEN1 (0.48) | RIPK1MEN1KMT2AATMHSP90AA1 | |
| SCHEMBL30989973 | 0.74 | RIPK1 (0.44) | RIPK1MEN1KMT2AATMHSP90AA1 | |
| SCHEMBL30989967 | 0.74 | RIPK1 (0.44) | RIPK1MEN1KMT2AATMHSP90AA1 | |
| SCHEMBL30989822 | 0.72 | RIPK1 (0.42) | RIPK1MEN1KMT2AATMHSP90AA1 | |
| SCHEMBL30989943 | 0.70 | MEN1 (0.39) | RIPK1MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL30989936 | 0.68 | RIPK1 (0.47) | RIPK1MEN1KMT2AALDH1A1MAOB | |
| SCHEMBL22841128 | 0.65 | RIPK1 (0.56) | RIPK1MEN1KMT2AATMALDH1A1 | |
| SCHEMBL17882304 | 0.65 | RIPK1 (1.00) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |