Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 8/20 | 0.48 |
| ▸ | SPR | P35270 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GPR6 | P46095 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989803 | 1.00 | PIN1 (0.48) | PIN1SPRALDH1A1XBP1HTT | |
| SCHEMBL30989798 | 0.91 | PIN1 (0.42) | PIN1SPRGPR6TRPM8 | |
| SCHEMBL30990055 | 0.91 | PIN1 (0.42) | PIN1SPRGPR6TRPM8 | |
| SCHEMBL30989894 | 0.88 | SPR (0.47) | PIN1SPRALDH1A1XBP1HTT | |
| SCHEMBL30989842 | 0.88 | SPR (0.47) | PIN1SPRALDH1A1XBP1HTT | |
| SCHEMBL30989831 | 0.83 | MAPK1 (0.41) | PIN1GPR6 | |
| SCHEMBL30990026 | 0.83 | MAPK1 (0.41) | PIN1GPR6 | |
| SCHEMBL30989826 | 0.82 | GPR6 (0.39) | PIN1SPRGPR6TRPM8 | |
| SCHEMBL30990045 | 0.79 | GPR6 (0.38) | PIN1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30989853 | 0.78 | PDE4A (0.54) | ALDH1A1PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |