Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.42 |
| ▸ | GPR6 | P46095 | 5/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | SLC8A1 | P32418 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989798 | 1.00 | PIN1 (0.42) | PIN1GPR6TRPM8PIK3C3ACHE | |
| SCHEMBL30989826 | 0.91 | GPR6 (0.39) | PIN1GPR6TRPM8PIK3C3ACHE | |
| SCHEMBL30989803 | 0.91 | PIN1 (0.48) | PIN1GPR6TRPM8SPR | |
| SCHEMBL30989947 | 0.91 | PIN1 (0.48) | PIN1GPR6TRPM8SPR | |
| SCHEMBL30989805 | 0.80 | GPR6 (0.39) | GPR6PIK3C3SLC8A1JAK2NTRK1 | |
| SCHEMBL30989842 | 0.78 | SPR (0.47) | PIN1TRPM8SPRMGLL | |
| SCHEMBL30989859 | 0.78 | GPR6 (0.39) | GPR6PIK3C3NTRK1KDM4C | |
| SCHEMBL30989838 | 0.78 | GPR6 (0.39) | GPR6PIK3C3NTRK1KDM4C | |
| SCHEMBL30989894 | 0.78 | SPR (0.47) | PIN1TRPM8SPRMGLL | |
| SCHEMBL30990026 | 0.78 | MAPK1 (0.41) | PIN1GPR6PIK3C3KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |