SCHEMBL30990249

SCHEMBL30990249

COC(=O)c1[nH]c2ccoc2c1SCc1ccc(OC)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TUBB4A P04350 5/20 0.42
▸ TUBB P07437 5/20 0.42
▸ TUBA3C P0DPH7 5/20 0.42
▸ TUBA1B P68363 5/20 0.42
▸ TUBA4A P68366 5/20 0.42
▸ TUBB4B P68371 5/20 0.42
▸ TUBB3 Q13509 5/20 0.42
▸ TUBB2A Q13885 5/20 0.42
▸ TUBB8 Q3ZCM7 5/20 0.42
▸ TUBA3E Q6PEY2 5/20 0.42
▸ TUBA1A Q71U36 5/20 0.42
▸ TUBA1C Q9BQE3 5/20 0.42
▸ TUBB6 Q9BUF5 5/20 0.42
▸ TUBB2B Q9BVA1 5/20 0.42
▸ TUBB1 Q9H4B7 5/20 0.42
▸ ALDH1A1 P00352 2/20 0.39
▸ ALOX15 P16050 2/20 0.39
▸ HSD17B10 Q99714 2/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ USP2 O75604 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30990203 0.90 FFAR1 (0.43) ALDH1A1HSD17B10KDM4EGAAMAPT
SCHEMBL30990230 0.72 ALDH1A1 (0.46) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL30990200 0.72 DAO (0.43) ALDH1A1TP53MEN1KMT2ASMN1; SMN2
SCHEMBL8225320 0.70 KDM4E (0.38) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL1244015 0.69 KDM4E (0.38) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL1244909 0.69 CCNC (0.38) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL25392545 0.67 RAB9A (0.52) ALDH1A1HSD17B10KDM4EMAPTHPGD
SCHEMBL17080240 0.65 KDM4E (0.46) ALDH1A1KDM4EMAPTHPGDNPSR1
SCHEMBL30786136 0.65 KDM4E (0.46) ALDH1A1KDM4EMAPTHPGDNPSR1
SCHEMBL10789554 0.64 IDO1 (0.61) ALDH1A1SMN1; SMN2FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626860-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS ReWind Therapeutics NV (BE) 2025-10-08 — — EP disclosed
WO-2024115733-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS REWIND THERAPEUTICS NV (BE) 2024-06-06 — — WO disclosed
Send feedback