SCHEMBL30990203

SCHEMBL30990203

COc1ccc(CSc2c(C(=O)O)[nH]c3ccoc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ FFAR1 O14842 1/20 0.43
▸ CYP2C9 P11712 2/20 0.43
▸ CYP2C19 P33261 2/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ CYP2E1 P05181 1/20 0.43
▸ CYP3A4 P08684 1/20 0.43
▸ CYP2C8 P10632 1/20 0.43
▸ CYP2D6 P10635 1/20 0.43
▸ CYP2B6 P20813 1/20 0.43
▸ CTSB P07858 1/20 0.41
▸ KDM4E B2RXH2 4/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ ALDH1A1 P00352 3/20 0.40
▸ HPGD P15428 3/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ MAPT P10636 2/20 0.40
▸ GAA P10253 1/20 0.40
▸ GPR17 Q13304 1/20 0.40
▸ DHODH Q02127 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30990249 0.90 TUBB4A (0.42) FFAR1CYP2C9CYP2C19CYP1A2CYP2E1
SCHEMBL30990200 0.73 DAO (0.43) CYP2C9CYP2C19CYP1A2CYP2E1CYP3A4
SCHEMBL30990230 0.69 ALDH1A1 (0.46) KDM4EKMT2AMEN1ALDH1A1HPGD
SCHEMBL7491139 0.66 CTSB (0.44) FFAR1CYP2C9CYP2C19CYP1A2CYP2E1
SCHEMBL21110584 0.65 FFAR1 (0.48) FFAR1CYP2C9CYP2C19CYP1A2CYP2E1
SCHEMBL2707629 0.65 FFAR1 (0.68) FFAR1CYP2C9CYP2C19CYP1A2CYP2E1
SCHEMBL30786121 0.64 TP53 (0.50) FFAR1CYP2C9CYP2C19CYP1A2CYP3A4
SCHEMBL7504854 0.64 CYP2E1 (0.52) FFAR1CYP2C9CYP2C19CYP1A2CYP2E1
SCHEMBL30786123 0.64 TP53 (0.50) FFAR1CYP2C9CYP2C19CYP1A2CYP3A4
SCHEMBL3841049 0.64 FFAR1 (0.49) FFAR1CYP2C9CYP2C19CYP1A2CYP2E1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626860-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS ReWind Therapeutics NV (BE) 2025-10-08 — — EP disclosed
WO-2024115733-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS REWIND THERAPEUTICS NV (BE) 2024-06-06 — — WO disclosed
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