SCHEMBL30990200

SCHEMBL30990200

COc1ccc(CSc2c[nH]c3ccoc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ DAO P14920 1/20 0.43
▸ APP P05067 1/20 0.41
▸ NPC1 O15118 2/20 0.40
▸ RAB9A P51151 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ MEN1 O00255 1/20 0.40
▸ NFKB1 P19838 1/20 0.40
▸ NFKB2 Q00653 1/20 0.40
▸ RELA Q04206 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ MAOB P27338 3/20 0.39
▸ MAOA P21397 2/20 0.39
▸ TP53 P04637 1/20 0.38
▸ CA12 O43570 1/20 0.38
▸ CA1 P00915 1/20 0.38
▸ CA2 P00918 1/20 0.38
▸ CA9 Q16790 1/20 0.38
▸ LMNA P02545 3/20 0.37
▸ IDO1 P14902 3/20 0.37
▸ MMP13 P45452 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30990203 0.73 FFAR1 (0.43) DAOAPPNPC1RAB9AKMT2A
SCHEMBL30990249 0.72 TUBB4A (0.42) DAOAPPNPC1RAB9AKMT2A
SCHEMBL10687383 0.70 APP (0.58) DAOAPPNPC1RAB9AKMT2A
SCHEMBL30990222 0.67 FFAR1 (0.47) DAOKMT2AMEN1MAOBMAOA
SCHEMBL3228582 0.65 APP (0.82) DAOAPPNPC1RAB9AKMT2A
SCHEMBL8640975 0.65 TSHR (0.45) DAOAPPNPC1RAB9AKMT2A
SCHEMBL1145768 0.65 IDO1 (0.57) APPSMN1; SMN2MAOBMAOATP53
SCHEMBL7298052 0.64 POLB (0.65) APPNPC1RAB9AKMT2AMEN1
SCHEMBL12603762 0.64 RAB9A (0.51) APPNPC1RAB9AKMT2AMEN1
SCHEMBL19297784 0.63 APP (0.49) DAOAPPNPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4626860-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS ReWind Therapeutics NV (BE) 2025-10-08 — — EP disclosed
WO-2024115733-A1 FUSED PYRROLYL-SULFONAMIDE COMPOUNDS REWIND THERAPEUTICS NV (BE) 2024-06-06 — — WO disclosed
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