Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGH | Q92820 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.37 |
| ▸ | GABRD | O14764 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.37 |
| ▸ | GABRE | P78334 | 2/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.37 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106298 | 0.90 | FPR2 (0.34) | FPR2PPARDTSHRPLAU | |
| SCHEMBL3097954 | 0.88 | GGH (0.49) | GGHFOLH1RIMKLANAALAD2 | |
| SCHEMBL3098098 | 0.86 | FPR2 (0.43) | CA12CA1CA9FPR2PPARD | |
| SCHEMBL3100418 | 0.85 | PPARD (0.42) | CA12CA1CA9FPR2PPARD | |
| SCHEMBL3097963 | 0.85 | TSHR (0.34) | CA12CA1CA9FPR2PPARD | |
| SCHEMBL3091598 | 0.84 | PLAU (0.34) | FPR2PPARDTSHRPLAU | |
| SCHEMBL3099111 | 0.82 | CYP1A2 (0.33) | CA12CA1CA9HPGDSFPR2 | |
| SCHEMBL3102342 | 0.82 | CA2 (0.36) | GGHCA1FOLH1FPR2PPARD | |
| SCHEMBL3103505 | 0.81 | PPARD (0.40) | CA12CA1CA9FPR2PPARD | |
| SCHEMBL3095596 | 0.81 | CPB2 (0.36) | CA12CA1CA9HPGDSFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |