Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 14/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30993135 | 0.85 | CREBBP (0.43) | GPR119CREBBPBRD4 | |
| SCHEMBL17785576 | 0.80 | CREBBP (0.56) | CREBBPBRD4 | |
| SCHEMBL21903877 | 0.78 | UCHL1 (0.45) | GPR119UCHL1USP30CHRM4DRD2 | |
| SCHEMBL17799590 | 0.74 | ABHD6 (0.43) | GPR119BRD4UCHL1USP30CHRM4 | |
| SCHEMBL30992909 | 0.73 | CREBBP (0.69) | CREBBPBRD4 | |
| SCHEMBL30993155 | 0.73 | CREBBP (0.39) | GPR119CREBBPBRD4 | |
| SCHEMBL30992903 | 0.71 | CREBBP (0.41) | CREBBPBRD4 | |
| SCHEMBL23063853 | 0.70 | HDAC1 (0.52) | GPR119BRD4UCHL1USP30 | |
| SCHEMBL21056563 | 0.70 | CYP11B2 (0.53) | BRD4CSNK2A1 | |
| SCHEMBL21903933 | 0.69 | NR1H2 (0.43) | GPR119UCHL1USP30CHRM4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A9 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-08-02 | — | — | WO | disclosed |
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |