SCHEMBL30993452

SCHEMBL30993452

Cc1cc2c(O)cc(C(C)C)cc2n(C)c1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.40
PTGS1 P23219 1/20 0.40
CACNA1C Q13936 1/20 0.40
BRPF1 P55201 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
DAO P14920 1/20 0.35
KDM4E B2RXH2 4/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
MAPT P10636 2/20 0.34
THRB P10828 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HSD17B10 Q99714 1/20 0.34
TYR P14679 3/20 0.33
TTR P02766 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
EGFR P00533 1/20 0.33
RNASEH1 O60930 1/20 0.33
MDM4 O15151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30993671 0.79 BRD4 (0.39) BRPF1KDM4EALDH1A1HPGDMAPT
SCHEMBL31248687 0.75 TTR (0.39) TRPA1BRPF1DAOKDM4EALDH1A1
SCHEMBL31248602 0.73 RORC (0.35) BRPF1DAOKDM4EALDH1A1HPGD
SCHEMBL30993033 0.71 BRPF1 (0.32) BRPF1
SCHEMBL2268725 0.70 ALDH1A1 (0.59) TRPA1PTGS1CACNA1CKDM4EALDH1A1
SCHEMBL30480878 0.70 PRKDC (0.44) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL26547748 0.70 PRKDC (0.44) KDM4EALDH1A1HPGDMAPTHSD17B10
SCHEMBL26112688 0.68 PDE1B (0.38) BRPF1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL29471257 0.68 PDE1B (0.38) BRPF1KDM4EALDH1A1HPGDHSD17B10
SCHEMBL30480908 0.68 TTR (0.40) BRPF1DAOKDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 WO disclosed
WO-2024130095-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-06-20 WO disclosed