SCHEMBL30993671

SCHEMBL30993671

COc1cc(C(C)C)cc2c1cc(C)c(=O)n2C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 4/20 0.39
▸ BRD2 P25440 2/20 0.39
▸ BRD9 Q9H8M2 2/20 0.39
▸ BRD7 Q9NPI1 2/20 0.39
▸ CYP19A1 P11511 4/20 0.37
▸ NQO2 P16083 4/20 0.37
▸ BRPF1 P55201 3/20 0.37
▸ BRD1 O95696 2/20 0.37
▸ BRPF3 Q9ULD4 1/20 0.37
▸ ALDH1A1 P00352 3/20 0.37
▸ KDM4E B2RXH2 1/20 0.37
▸ GLA P06280 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ HDAC4 P56524 1/20 0.36
▸ HDAC8 Q9BY41 1/20 0.36
▸ TTR P02766 1/20 0.36
▸ MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30993033 0.79 BRPF1 (0.32) BRPF1BRD1BRPF3
SCHEMBL29471200 0.79 MEN1 (0.43) BRD4BRD2BRD9BRD7CYP19A1
SCHEMBL26547628 0.79 MEN1 (0.43) BRD4BRD2BRD9BRD7CYP19A1
SCHEMBL30993452 0.79 TRPA1 (0.40) BRPF1ALDH1A1KDM4EGLAHPGD
SCHEMBL31248987 0.77 PTGS2 (0.42) BRD4BRD2BRD9BRD7CYP19A1
SCHEMBL31248925 0.75 TTR (0.40) BRD4BRD2BRD9BRD7CYP19A1
SCHEMBL31248669 0.75 LMNA (0.46) BRD4BRD2BRD9BRD7BRPF1
SCHEMBL31248776 0.74 BRD4 (0.37) BRD4BRD2BRD9BRD7CYP19A1
SCHEMBL30993226 0.74 BRD4 (0.37) BRD4BRD2BRD9BRD7CYP19A1
SCHEMBL31426151 0.74 NQO2 (0.53) BRD4BRD2BRD9BRD7CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 — — EP disclosed
WO-2024249888-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2024-12-05 — — WO disclosed
WO-2024130095-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2024-06-20 — — WO disclosed
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