Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.39 |
| ▸ | INSR | P06213 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30993716 | 0.73 | CREBBP (0.41) | KMT2ANPC1 | |
| SCHEMBL30993024 | 0.72 | TYK2 (0.42) | NPC1 | |
| SCHEMBL30993751 | 0.70 | POLB (0.36) | NPC1HPGDPOLB | |
| SCHEMBL824836 | 0.70 | SMN1; SMN2 (0.50) | HTTSMN1; SMN2MAPK1MAPTLMNA | |
| SCHEMBL30993612 | 0.70 | POLB (0.37) | SMN1; SMN2KMT2ANPC1POLB | |
| SCHEMBL10153998 | 0.67 | ALDH1A1 (0.51) | SMN1; SMN2LMNAKMT2AMEN1RAB9A | |
| SCHEMBL17979816 | 0.66 | MAPT (0.54) | HTTSMN1; SMN2MAPK1MAPTLMNA | |
| SCHEMBL21549442 | 0.66 | SMN1; SMN2 (0.50) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL241043 | 0.65 | PIK3CB (0.57) | HTTSMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL30993430 | 0.64 | GAA (0.43) | SMN1; SMN2MAPK1MAPTPTK2PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |