Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | HAT1 | O14929 | 1/20 | 0.33 |
| ▸ | EP300 | Q09472 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 3/20 | 0.33 |
| ▸ | CHUK | O15111 | 2/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.33 |
| ▸ | F3 | P13726 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30993716 | 0.78 | CREBBP (0.41) | PYGLNR4A2NHERF1NPC1HAT1 | |
| SCHEMBL30993751 | 0.75 | POLB (0.36) | PYGLNR4A2NHERF1NPC1HAT1 | |
| SCHEMBL30993612 | 0.75 | POLB (0.37) | TYK2PYGLNR4A2NHERF1NPC1 | |
| SCHEMBL30993573 | 0.72 | HTT (0.39) | NPC1 | |
| SCHEMBL30993163 | 0.68 | CREBBP (0.39) | PDK2CD38PYGLNR4A2NPC1 | |
| SCHEMBL31375034 | 0.66 | F7 (0.51) | NR4A2NHERF1NPC1F7F3 | |
| SCHEMBL14540389 | 0.66 | CHRM1 (0.47) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22272971 | 0.66 | TYK2 (0.42) | TYK2SLC6A4CNR2 | |
| SCHEMBL27648661 | 0.65 | BRPF1 (0.39) | PYGLNR4A2NHERF1NPC1F7 | |
| SCHEMBL30993273 | 0.65 | AR (0.34) | CD38PYGLNR4A2NPC1HAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |