Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700904 | 0.79 | PTGDR2 (0.41) | PTGS2PTGDR2ADRA2AHTR1DHTR1B | |
| SCHEMBL42781 | 0.73 | PTGDR2 (0.48) | PTGS2PTGDR2ADRA2AHTR1DHTR1B | |
| SCHEMBL16335849 | 0.72 | HTR2C (0.44) | PTGS2PTGDR2ADRA2AHTR1AUSP2 | |
| SCHEMBL2364217 | 0.71 | BCHE (0.30) | BCHEACHE | |
| SCHEMBL30480018 | 0.71 | MAPK1 (0.32) | ALDH1A1ACHE | |
| SCHEMBL779938 | 0.71 | CHRNB4 (0.46) | PTGS2PTGDR2HTR1AHTR1DHTR1B | |
| SCHEMBL1315082 | 0.71 | MAPK1 (0.32) | ALDH1A1ACHE | |
| SCHEMBL31321456 | 0.70 | CYP3A4 (0.41) | PTGS2PTGDR2DRD1HTR1DHTR1B | |
| Bromide SCHEMBL31016464 | 0.70 | PTGDR2 (0.39) | PTGS2PTGDR2DRD1MEN1KMT2A | |
| Hydrogen Peroxide SCHEMBL3679819 | 0.69 | PTGDR2 (0.55) | PTGS2PTGDR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1864714-B1 | Process for producing arylamine | TOSOH CORP (JP) | 2016-11-23 | — | — | EP | disclosed |
| US-7803953-B2 | Catalyst for producing arylamine and process for producing arylamine by means thereof | TOSOH CORPORATION (JP) | 2010-09-28 | — | — | US | disclosed |
| US-7560582-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-07-14 | — | — | US | disclosed |
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-02-07 | — | — | US | disclosed |
| EP-1864714-A1 | Catalyst for producing arylamine and process for producing arylamine by means thereof | Tosoh Corporation (JP) | 2007-12-12 | — | — | EP | disclosed |
| US-20070282111-A1 | Catalyst for producing arylamine and process for producing arylamine by means thereof | TOSOH CORPORATION (JP) | 2007-12-06 | — | — | US | disclosed |
| US-7247731-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-07-24 | — | — | US | disclosed |
| US-7223879-B2 | Ligands for metals and improved metal-catalyzed processes based thereon | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2007-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080033171-A1 | Ligands for Metals and Improved Metal-Catalyzed Processes Based Thereon | THEM6, SOD1, SLC30A6 | PTGS2 1882/4885PTGDR2 4500/4885ADRA2A 4531/4885 |
| US-20070282111-A1 | Catalyst for producing arylamine and process for producing arylamine by means thereof | TYR, PNMT, INMT | PTGS2 3413/4885PTGDR2 2317/4885ADRA2A 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.