SCHEMBL30995334

SCHEMBL30995334

COc1ccc(COc2c(F)cc(C(=O)NCC34CCC(c5nc(-c6ccnc(SC)n6)cs5)(CC3)CC4)c(F)c2F)cc1

nearest known ligand 0.32

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 1/20 0.32
P2RX7 Q99572 3/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
DPP4 P27487 1/20 0.31
ROCK2 O75116 1/20 0.30
ROCK1 Q13464 1/20 0.30
KLKB1 P03952 1/20 0.30
CNR2 P34972 1/20 0.30
ABHD6 Q9BV23 1/20 0.30
PIK3CA P42336 1/20 0.30
P2RY12 Q9H244 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29319440 1.00 CSF1R (0.32) CSF1RP2RX7MEN1KMT2ADPP4
SCHEMBL30995403 0.89 SLC6A9 (0.32) CSF1RP2RX7MEN1KMT2ADPP4
SCHEMBL29319434 0.89 SLC6A9 (0.32) CSF1RP2RX7MEN1KMT2ADPP4
SCHEMBL29319429 0.83 ACHE (0.37)
SCHEMBL30995409 0.83 ACHE (0.37)
SCHEMBL27391240 0.76 P2RX7 (0.40) P2RX7KLKB1P2RY12
SCHEMBL27213785 0.76 P2RX7 (0.40) P2RX7KLKB1P2RY12
SCHEMBL30995282 0.75 P2RX7 (0.40) P2RX7P2RY12
SCHEMBL29317998 0.75 P2RX7 (0.41) P2RX7P2RY12
SCHEMBL29318715 0.75 P2RX7 (0.40) P2RX7P2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634169-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF Pfizer Inc. (US) 2025-10-22 EP disclosed
WO-2024127297-A1 3-FLUORO-4-HYDROXYBENZMIDE-CONTAINING INHIBITORS AND/OR DEGRADERS AND USES THEREOF PFIZER INC. (US) 2024-06-20 WO disclosed