Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK1 | P51617 | 3/20 | 0.48 |
| ▸ | IRAK3 | Q9Y616 | 3/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 3/20 | 0.38 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | CCNC | P24863 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26139423 | 0.93 | CRBN (0.47) | IRAK1IRAK3ITGB3ITGA2BALOX15 | |
| SCHEMBL30042811 | 0.93 | CRBN (0.47) | IRAK1IRAK3ITGB3ITGA2BALOX15 | |
| SCHEMBL27463020 | 0.85 | ITGB3 (0.48) | IRAK1IRAK3ITGB3ITGA2BALOX15 | |
| SCHEMBL27176453 | 0.83 | CRBN (0.48) | IRAK1IRAK3ALOX15CRBNKMT2A | |
| SCHEMBL30996484 | 0.83 | CRBN (0.66) | IRAK1IRAK3ITGB3ITGA2BALOX15 | |
| SCHEMBL29522041 | 0.82 | CRBN (0.46) | IRAK1IRAK3ALOX15CRBNKMT2A | |
| SCHEMBL29522052 | 0.82 | CRBN (0.46) | IRAK1IRAK3ALOX15CRBNKMT2A | |
| SCHEMBL29129961 | 0.82 | IRAK1 (0.47) | IRAK1IRAK3ALOX15CRBNKMT2A | |
| SCHEMBL25901414 | 0.79 | CRBN (0.53) | IRAK1IRAK3ALOX15CRBNKMT2A | |
| SCHEMBL24501060 | 0.77 | CRBN (0.54) | IRAK1IRAK3ITGB3ITGA2BALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024145315-A1 | TARGETED PROTEIN DEGRADERS OF INDOLEAMINE 2,3-DIOXYGENASE 1 (IDO1) | NORTHWESTERN UNIVERSITY (US) | 2024-07-04 | — | — | WO | disclosed |