Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23275100 | 0.89 | PKM (0.40) | PKMPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL26121604 | 0.86 | PKM (0.38) | PKMPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL20555375 | 0.84 | PDE1C (0.42) | POLBALDH1A1CYP2C9 | |
| SCHEMBL15995596 | 0.82 | ALOX15 (0.50) | PKMPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL17610427 | 0.82 | CHRNB2 (0.41) | PKMPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL16985293 | 0.82 | POLB (0.38) | PKMPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL30996621 | 0.82 | NR3C1 (0.37) | PKMPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL30996608 | 0.81 | PKM (0.35) | PKMPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL20555241 | 0.80 | PKM (0.41) | PKMPOLBL3MBTL1MEN1KMT2A | |
| SCHEMBL31121567 | 0.79 | PDE1C (0.41) | ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024179393-A1 | SULFOXIMINE COMPOUNDS AND APPLICATION THEREOF AS LRRK2 PROTEIN KINASE INHIBITORS | 科辉智药(深圳)新药研究中心有限公司 | 2024-09-06 | — | — | WO | disclosed |
| CN-118546132-A | Sulfoxide imide compound and application thereof as LRRK2 protein kinase inhibitor | 科辉智药(深圳)新药研究中心有限公司 | 2024-08-27 | — | — | CN | disclosed |