Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30997271 | 0.84 | MAPK14 (0.39) | MAPTGAASMN1; SMN2KMT2ATP53 | |
| SCHEMBL11328355 | 0.81 | TGFBR1 (0.40) | MAPTKMT2ANPC1KDM4EPOLB | |
| SCHEMBL31003054 | 0.70 | KDM4E (0.39) | MAPTHTTKMT2ANPSR1MAPK1 | |
| SCHEMBL15813304 | 0.70 | KDM4E (0.39) | MAPTHTTKMT2ANPSR1MAPK1 | |
| SCHEMBL286156 | 0.66 | ALDH1A1 (0.45) | GAASMN1; SMN2HTTKMT2AMEN1 | |
| SCHEMBL20125014 | 0.65 | MAPT (0.51) | MAPTGAASMN1; SMN2HTTKMT2A | |
| SCHEMBL28619424 | 0.64 | PTGS2 (0.40) | MAPTSMN1; SMN2KMT2ATDP1MEN1 | |
| SCHEMBL15345055 | 0.64 | NPC1 (0.44) | MAPTGAASMN1; SMN2HTTKMT2A | |
| SCHEMBL15173172 | 0.63 | ERN1 (0.43) | MAPTSMN1; SMN2HTTTDP1TP53 | |
| SCHEMBL28791184 | 0.62 | KDM4E (0.42) | MAPTSMN1; SMN2HTTTDP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118556061-A | Disubstituted octahydropyrrolo [3,4-c ] pyrrole methyl ketone derivative and application thereof | 江苏恩华药业股份有限公司 | 2024-08-27 | — | — | CN | disclosed |