SCHEMBL30997372

SCHEMBL30997372

Fc1cnccc1CNc1nc(Cl)nn2c(Br)ccc12

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KCNH3 Q9ULD8 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.35
BUB1 O43683 1/20 0.32
TGFBR1 P36897 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30997392 0.86 KCNH3 (0.41) KCNH3LOXL2BUB1TGFBR1
SCHEMBL30948887 0.85 MEN1 (0.42)
SCHEMBL30997381 0.80 KCNH3 (0.40) KCNH3LOXL2TGFBR1
SCHEMBL30997364 0.77 KCNH3 (0.38) KCNH3
SCHEMBL30997368 0.77 KCNH3 (0.34) KCNH3LOXL2
SCHEMBL31030141 0.76
SCHEMBL30948921 0.74 PDE5A (0.49)
SCHEMBL30948898 0.72 MEN1 (0.43)
SCHEMBL31010616 0.72 HRH4 (0.39)
SCHEMBL31030096 0.71 SMN1; SMN2 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651950-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING Skyhawk Therapeutics, Inc. (US) 2025-11-26 EP disclosed
WO-2024155842-A1 COMPOSITIONS USEFUL FOR MODULATING SPLICING SKYHAWK THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed