Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | RAD52 | P43351 | 2/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | NCF1 | P14598 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22450644 | 0.88 | MAPT (0.56) | MAPTKDM4ERAD52ADRA2CGAA | |
| SCHEMBL29310093 | 0.79 | DRD2 (0.42) | MAPTKDM4EGAAALDH1A1PTK2B | |
| SCHEMBL22635909 | 0.78 | NCF1 (0.58) | MAPTKDM4EADRA2CKMT2AMAPK1 | |
| SCHEMBL1397389 | 0.76 | DRD2 (0.60) | MAPTKDM4ERAD52ADRA2CGAA | |
| Hydrochloric Acid SCHEMBL6345252 | 0.75 | KDM4E (0.59) | MAPTKDM4ERAD52ADRA2CGAA | |
| Hydrochloric Acid SCHEMBL6343779 | 0.75 | KDM4E (0.59) | MAPTKDM4ERAD52ADRA2CGAA | |
| SCHEMBL29310423 | 0.74 | HTR1A (0.43) | MAPTKDM4ERAD52ALDH1A1POLB | |
| SCHEMBL429632 | 0.74 | MAPT (0.62) | MAPTKDM4ERAD52ADRA2CGAA | |
| SCHEMBL23567036 | 0.74 | MAPT (0.54) | MAPTKDM4ERAD52ADRA2CGAA | |
| SCHEMBL30736195 | 0.74 | MAPT (0.54) | MAPTKDM4ERAD52ADRA2CGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | BOUNDLESS BIO, INC. | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240228459-A1 | WEE1 INHIBITORS AND USES THEREOF | WEE1, WEE2, DCLRE1B | MAPT 3813/4885KDM4E 360/4885RAD52 293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.