Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30998040 | 1.00 | POLB (0.54) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL2845366 | 1.00 | POLB (0.54) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL2849735 | 0.92 | TSHR (0.54) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL2905614 | 0.84 | GAA (0.56) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL9232355 | 0.84 | GAA (0.56) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10600761 | 0.80 | NPC1 (0.56) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL1888725 | 0.79 | ALDH1A1 (0.51) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL5443614 | 0.79 | CA1 (0.43) | ALDH1A1TSHRLMNATRPV4 | |
| SCHEMBL826419 | 0.77 | L3MBTL1 (0.44) | ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL29410051 | 0.77 | L3MBTL1 (0.44) | ALDH1A1TSHRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852054-A | Benzothiadiazepines cycloheptatriene compounds Compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2024-10-29 | — | — | CN | disclosed |
| CN-113677398-B | Benzothiadiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2024-07-23 | — | — | CN | disclosed |