Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30998040 | 1.00 | POLB (0.54) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL30998038 | 1.00 | POLB (0.54) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL2849735 | 0.92 | TSHR (0.54) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL2905614 | 0.84 | GAA (0.56) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL9232355 | 0.84 | GAA (0.56) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL10600761 | 0.80 | NPC1 (0.56) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL1888725 | 0.79 | ALDH1A1 (0.51) | POLBALDH1A1GAAKDM4EMAPT | |
| SCHEMBL5443614 | 0.79 | CA1 (0.43) | ALDH1A1TSHRLMNATRPV4 | |
| SCHEMBL826419 | 0.77 | L3MBTL1 (0.44) | ALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL29410051 | 0.77 | L3MBTL1 (0.44) | ALDH1A1TSHRLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250326728-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2025-10-23 | — | — | US | disclosed |
| US-12187690-B2 | Benzothiadiazepine compounds and their use as bile acid modulators | ALBIREO AB (SE) | 2025-01-07 | — | — | US | disclosed |
| US-20230406832-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2023-12-21 | — | — | US | disclosed |
| US-11603359-B2 | Benzothiadiazepine compounds and their use as bile acid modulators | ALBIREO AB (SE) | 2023-03-14 | — | — | US | disclosed |
| EP-3921028-B1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2022-11-09 | — | — | EP | disclosed |
| EP-3921028-B1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2022-11-09 | — | — | EP | disclosed |
| EP-3921028-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | Albireo AB (SE) | 2021-12-15 | — | — | EP | disclosed |
| CN-113677398-A | Benzothiadiazepine compounds and their use as bile acid modulators | 阿尔比里奥公司 | 2021-11-19 | — | — | CN | disclosed |
| US-20210179572-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2021-06-17 | — | — | US | disclosed |
| US-20210179572-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2021-06-17 | — | — | US | disclosed |
| WO-2020161217-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020161217-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2020-08-13 | — | — | WO | disclosed |
| US-20200247769-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2020-08-06 | — | — | US | disclosed |
| US-20200247769-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | ALBIREO AB (SE) | 2020-08-06 | — | — | US | disclosed |
| US-20120251919-A1 | POLYARYLENE-BASED COPOLYMER AND USES THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-04 | — | — | US | disclosed |
| EP-2489690-A1 | POLYARYLENE COPOLYMER AND USES THEREOF | Sumitomo Chemical Company Limited (JP) | 2012-08-22 | — | — | EP | disclosed |
| US-20100129729-A1 | CEOSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE,CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL | SUMITOMO CHEMICAL COMPANY ,LIMITED | 2010-05-27 | — | — | US | disclosed |
| EP-2147943-A1 | CROSSLINKED AROMATIC POLYMER, POLYMER ELECTROLYTE, CATALYST INK, POLYMER ELECTROLYTE MEMBRANE, MEMBRANE-ELECTRODE ASSEMBLY AND FUEL CELL | Sumitomo Chemical Company, Limited (JP) | 2010-01-27 | — | — | EP | disclosed |
| US-20090253015-A1 | POLYARYLENE BLOCK COPOLYMER AND USE THEREOF | SUMITOMO CHEMICAL COMPANY ,LIMITED (JP) | 2009-10-08 | — | — | US | disclosed |
| EP-1857482-A1 | POLYARYLENE BLOCK COPOLYMER AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2007-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247769-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | POLB 4689/4885ALDH1A1 580/4885GAA 637/4885 |
| US-11603359-B2 | Benzothiadiazepine compounds and their use as bile acid modulators | SLC10A1, SLC10A2, ABCB11 | POLB 4689/4885ALDH1A1 580/4885GAA 637/4885 |
| US-20250326728-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | POLB 4689/4885ALDH1A1 580/4885GAA 637/4885 |
| US-20210179572-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | POLB 4689/4885ALDH1A1 580/4885GAA 637/4885 |
| US-12187690-B2 | Benzothiadiazepine compounds and their use as bile acid modulators | SLC10A1, SLC10A2, ABCB11 | POLB 4689/4885ALDH1A1 580/4885GAA 637/4885 |
| US-20230406832-A1 | BENZOTHIADIAZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS | SLC10A1, SLC10A2, ABCB11 | POLB 4689/4885ALDH1A1 580/4885GAA 637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.