Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5119617 | 1.00 | MAPT (0.55) | MAPTALDH1A1LMNAUSP30MET | |
| SCHEMBL3977939 | 0.91 | ALDH1A1 (0.47) | MAPTALDH1A1LMNAUSP30MET | |
| SCHEMBL5093442 | 0.86 | MAPT (0.70) | MAPTALDH1A1LMNAHTTNR1H2 | |
| SCHEMBL985189 | 0.84 | LMNA (0.73) | MAPTALDH1A1LMNAMETMEN1 | |
| SCHEMBL22650344 | 0.84 | NR1H2 (0.53) | MAPTALDH1A1LMNAUSP30KDM4E | |
| SCHEMBL30208112 | 0.84 | LMNA (0.73) | MAPTALDH1A1LMNAMETMEN1 | |
| SCHEMBL30998085 | 0.84 | NR1H2 (0.53) | MAPTALDH1A1LMNAUSP30KDM4E | |
| SCHEMBL5891913 | 0.84 | P2RX7 (0.58) | MAPTUSP30MEN1KMT2AENPP2 | |
| SCHEMBL3974873 | 0.83 | MEN1 (0.48) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL3974870 | 0.83 | MEN1 (0.48) | MAPTALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234726-A | Chimeric compound for androgen receptor protein targeted degradation, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2024-06-21 | — | — | CN | disclosed |